Confused about Monoclonal Antibody Treatments? So was I.

A lot of people have asked, and since I have done some amount of personal research on this here’s what I’ve learned about the various monoclonal antibody treatments.

Due to a close-contact Covid exposure before Christmas, my transplant team recommended I get a monoclonal treatment. They sent me to the Florida State-run free monoclonal infusion website and I made an appointment and went last Wednesday and got the Regen-Cov infusion.

Currently in the US (as of 1/5/2022), there are four different approved monoclonal antibody infusions:

  • Regeneron – REGEN-COV (Casirivimab and Imdevimab) – 4 injections, each arm and 2 in stomach
  • Eli Lily – (Bamlanivimab and Etesevimab) – Administered via IV.
  • GlaxoSmithKlein – (Sotrovimab) – Administered via IV
  • AstraZeneca – Evusheld (Tixagevimab/Cilgavimab) – 2 intramuscular injections

As of last week, Florida was only distributing Regeneron and the Eli Lily brands. The GSK one is the version that data points to being the most effective against Omicron, but you can’t just assume you know which variant you have or been exposed to. Unless you’re doing some fancy test that the rest of us don’t have access to, the particular flavor of Covid anyone has is an unknown. While Omicron is the most common out there at the moment, there is still plenty of Delta around.

The AstraZeneca one isn’t recommended for people who have Covid or been exposed, but as a preventative for immunocompromised people who for whatever reason can’t do vaccines.

Like I said, I got the Regeneron 4 shot injection. After the injections I waited in the waiting area for about 30 minutes for observation before I was told I could leave. I didn’t notice any side effects at all.

Hope this info helps someone!

Florida Monoclonal Antibody Website

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